Phentermine Reviews
Phentermine is a drug under the amphetamine and phenethylamine class. It is not an amphetamine. In 1959, the FDA approved this substance as an appetite suppressant drug and since then has been widely used to help obese patients to suppress hunger and lose weight.
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Ingredients and Mechanism of Action
Phentermine, like many other prescription drugs, is a centrally acting drug. This means that it works in the brain by stimulating neuron bundles to release a particular group of neuotransmitters known as catecholamines. These include dopamine, epinephrine, norepeinephrine. The catecholamines excite the sympathetic part of the nervous system-the fight or flight response. In turn, it inhibits the hunger signal causing an appetite suppression.
Effectiveness and Use of Phentermine
Studies have shown that Phentermine causes a 10-15 % greater weight loss compared to a placebo in a double-blind study. Like most diet pills, its effectiveness will be greatest if accompanied by proper diet and exercise. Phentermine is most effective if taken once a day during a 3-4 week period.
It is best to take Phentermine before 3pm due to the risk of insomnia. It is recommended to take Phentermine on an empty stomach, usually before breakfast or 1-2 hours after breakfast.
Safety Issues of Phentermine
You should not take Phentermine if you are also taking dexfenfluramine, fenfluramine, furazolidone, guanadrel, guanethidine, or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) in the last 14 days.
People with severe high blood pressure, an overactive thyroid, glaucoma, heart or blood vessel disease, or severe narrowing of the blood vessels should not take Phentermine.
Some people may have allergic reactions with any of the ingredients in Phentermine.
Phentermine should not be prescribed to women that are pregant or breastfeeding and should not be prescribed to children under the age of 16.
Possible Side Effects of Phentermine
Generally, Phentermine appears to be relatively well tolerated. Because it releases catecholamines, its possible side effects are simply the effects of having too much adrenaline and noradrenaline. Such possible side effects are tachycardia (increased heart rate) and elevated blood pressure, but the incidence and magnitude of these appear to be less than with amphetamines. The drug may increase blood pressure and heart rate. It may also cause dry mouth, constipation, diarrhea, restlessness, and insomnia.
Overall Impression of Phentermine:
Phentermine was approved by the FDA in 1959 to control appetite. FDA approved means that it is one of the most powerful appetite suppressants in the market that is still considered safe to use and well tolerated. Many research and clinical studies have proven this to be an effective weight loss substance when accompanied with diet and exercise. It is recommended for the consumer to closely monitor any possible side effects during the first few days of use.
