's Top-Rated Diet Pill of 2019

Overall Value: 99/100

Apidren contains clinically proven ingredients that work together to burn your excess body fat and suppress appetite to make eating less easier. Backed by a 100% Money Back Guarantee, Apidren is the clear #1 choice to help you lose weight fast and keep it off for good!

Click Here to Learn More About Apidren »

Kimberly Tenner
November 29, 2019

BiphedAdrene Review


BiphedAdrene is said to be the “current leader” in a new category of “high-quality, super-powerful, and super-effective” diet pills hitting the shelves of your local GNC.

With a two-pronged attack against fat, BiphedAdrene supposedly takes mood and fat burning capabilities to new levels.

According to Tiffany Strobel, beauty editor, “this two-pronged attack on fat is apparently what makes the compound so effective. . .and so popular.”

However, manufacturers warn this new diet pill isn’t for everyone. “You shouldn’t even think about taking them if losing five or six ‘vanity pounds’ is your goal. These diet pills are intended exclusively for the significantly overweight.”

This all sounds pretty convincing, but I’m still not sold on BiphedAdrene. Is this formula really as powerful as it sounds?

Let’s take a closer look at the two formulas and whether they can live up to the hype.

A Closer Look at the Purple Pill

Manufacturers call this formula the “Complex Penylethylamine Provisional.” It contains a 489 mg blend of the following ingredients:

Trimethylxanthine – the scientific name for caffeine. It increases energy levels.
Paullinia Cupana – the scientific name for guarana. It contains caffeine.
Caffeine – see trimethylxanthine.
Arbutin – a damiana extract. It may act as a diuretic.
Phenylethylamine – also known as PEA. It enhances mood and increases energy.
Pheylethan-2-amine – the scientific name for PEA.
Methylbenzylamine – the scientific name for 1-phenylethylamine, a PEA derivative.
Phenethylamine – another name for PEA.
1-Phenylethylamine – see methylbenzlamine.
Theobromine – a chemical similar in structure to caffeine. It boosts energy levels.

It also contains a 15 mg dose of Niacin, or vitamin B3.

Inside the Yellow Pill

Manufacturers call this formula the “Aggressive Thermogenic Compound.” It contains a 489 mg blend of the following ingredients:

Ilex Paraguarinensis – the scientific name for yerba mate. It contains caffeine.
Guarana – another source of caffeine.
Methylxanthin – the scientific name for caffeine anhydrous, a dehydrated form of caffeine.
Tumera Diffusa var. Aphrodisiaca – the scientific name for damiana. It acts as an aphrodisiac and mood enhancer.
Capsaicin – a chili pepper extract that stimulates thermogenesis.
Serotonin – a neurotransmitter responsible for appetite and mood regulation.
L-Dopa – a dopamine precursor. It is associated with reward-seeking behaviors.

Are Both Pills Safe?

Scientific mumbo jumbo aside, both pills are basically a combination of caffeine, PEA, and one or two extra ingredients that either boost mood or energy.

These ingredients are considered safe when used correctly, but whether BiphedAdrene utilizes these ingredients properly is unknown.

According to the label, “this product contains a significantly potent xanthine (stimulants) mixture of approximately 300 mg per serving.”

The directions state dieters are to take one of each tablet before their main meals. This totals to 600 mg of stimulants taken three times daily, or 1800 mg of stimulants a day.
Depending on your sensitivity to stimulants, this could give you an effective boost in energy. . . .or it could wreak havoc on your body.

Caffeine alone is known to cause side effects such as headaches, dizziness, nausea, upset stomach, insomnia, rapid or irregular heartbeat, etc.

Combine that with PEA, which can trigger heartburn, nausea, constipation, and headaches. Mix in L-Dopa, which cause extreme emotional states, and you’ve got yourself a cocktail for a rather unpleasant experience.

Consequently, you’ll want to adjust your dosage to suit your needs.

Jeneishadavis shares her experience on, “The product seems to be ok, day 1 i took the pills twice a day & it made me very sick. Vomiting & mild headaches & didn’t get much sleep, I did drink plenty of water. Tried it again on day 2, I only took it once that day & i wasn’t sick, vomiting & no headaches & slept very well. Today is day 3 & i’m gonna continue to take the product once a day for the next week & let my body adjust to it before trying to take it twice a day again…”

How to Take BiphedAdrene

The label gives us two instructions for use –

For weight loss: take one yellow capsule and one purple tablet together 15 minutes before main meals.

For a significant energy boost: take one yellow capsule and one purple tablet together as needed.

On the other hand, considering how many stimulants are in this formula, I suggest dieters start off slowly. Take a one tablet of each formula per day for the first few days to assess tolerance. If you think you can handle the ingredients, you can take an additional serving 6 hours later. Then, as your body adjusts, you can take the maximum dosage of 3 servings of each formula per day.

• Do not exceed more than one purple tablet and one yellow capsule in any 4 hour period

• Do not exceed more than 3 purple tablets and 3 yellow tablets in a 24 hour period

• Do not consume caffeine from additional sources (such as coffee, tea, and soda)

• Do not use BiphedAdrene if you have the following conditions: high blood pressure, cardiovascular disease, thyroid disease, seizure disorder, diabetes, recurrent headaches, depression, or other psychiatric conditions.

Pricing Options

For a caffeine pill, BiphedAdrene is fairly expensive, selling for $135 per 30 day supply at

Even if you shop around at various online stores, the product is still more than the average diet pill:

• $135
• $74.97
• $72.99

If you prefer to buy directly from the manufacturers so you can qualify for the guarantee, you can get an additional discount by typing the code INSTOCK into the promotional code box when checking out.

High demand for BiphedAdrene has made it difficult for manufacturers to keep the product on the shelves. Consequently, the manufacturers are providing $25 discounts as a way of apology. The code was still valid as of November 8, 2012.

Is It Refundable?

The 100% money-back guarantee at is a little confusing. According to the website, if you are not satisfied with your results, you can return it “to the place of purchase within 30 days.”

What does that mean? Does it mean you can return your order and they have to honor the guarantee? Or does the “place of purchase” only apply to products purchased at

Additionally, there is no contact information available at – so if you want to make a return, you’ll have to go elsewhere.

Fortunately, does offer a 30 day guarantee on all its products, which is clearly explained on its terms and conditions page.

More about Generix Labs

BiphedAdrene LLC, is a division of Generix Laboratories LLC. The company is based in Salt Lake City , UT, and offers several other weight loss products, including Leptopril.

According to the Better Business Bureau, the company received an F rating on a scale of A+ to F – that’s the lowest score possible! The company received this rating for the following reasons:

• “BBB concerns with the industry in which this business operates.”

• “Advertising issue(s) found by BBB.”

• “BBB does not have sufficient background information on this business. BBB made two or more requests for background information from the business. BBB has not received a response from this business and/or has not been able to verify information received from this business.”

Additionally, the BBB gives us the following background information:

“On April 3, 2012 the BBB contacted this company and requested substantiation of the company’s claims including “Weight Loss”, “Sustained Energy & Stamina” and “Mood Enhancement”. The BBB also requested substantiation for any claims that offer the following FDA disclaimer: “This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.” The BBB requested substantiation based upon the standards outlined in the BBB Code of Advertising. The BBB substantiation request also required a fee of $100 fee for review of these claims. As of May 30, 2012 the company has failed to respond to BBB requests for substantiation.”

Due to the lack of substantiation, the NAD (National Advertising Division, an investigative group of the BBB) referred the matter to the FTC for further review.

Is BiphedAdrene Worth the Price?

$70 or more for a caffeine pill? No thank you.

I prefer to recommend diet pills with a clinically proven blend of appetite suppressants, fat burners, and metabolism boosters. While BiphedAdrene seems to provide weight loss results for a few individuals, I do not feel comfortable giving this product a thumbs-up due to the high risk of negative side effects and the unreliable manufacturers.

You’d be better off investing in a formula designed with your overall health in mind.

BiphedAdrene Customer Reviews

Click Here to Read BiphedAdrene Customer Reviews »

Have You Used BiphedAdrene? Write a Review!

Will not be published or shared in any way. (Privacy Policy)

See 2019 Editor's Choice »